POTS and MCAS can coexist, but current research does not establish that one causes the other or that MCAS is unusually common in...
Hyperadrenergic POTS describes a POTS phenotype with excessive sympathetic activation, often including raised upright norepinephrine or blood-pressure responses, though phenotype boundaries can overlap.
MCAS and histamine intolerance can look strikingly similar, but they describe different proposed mechanisms and require different types of evidence.