Hormones & Metabolism

Guides on estrogen, progesterone, cortisol, stress, inflammation, metabolism, and midlife symptom patterns.

4 Articles
Technical illustration of PMDD and histamine showing brain signaling, menstrual cycle hormones and mast-cell activity
Menstrual Cycle & Reproductive Hormones

PMDD and Histamine: Is There Really a Connection?

PMDD appears to reflect abnormal brain sensitivity to normal hormone shifts; histamine may overlap, but it has not been shown to cause the...

Technical illustration of histamine and menopause showing hormones, mast cells, gut, skin and brain
Menstrual Cycle & Reproductive Hormones

Histamine and Menopause: Can Hormonal Changes Affect Histamine Intolerance?

Menopause can change immune, vascular and mast-cell biology, but current evidence does not show that menopause directly causes dietary histamine intolerance.

Watercolor illustration of a woman tracking menstrual symptoms related to estrogen and histamine
Menstrual Cycle & Reproductive Hormones

Estrogen and Histamine: How Strong Is the Hormone Connection?

Estrogen can affect mast-cell signaling, but the popular estrogen–histamine feedback-loop theory goes further than current human evidence can prove.

Can histamine intolerance cause weight gain? Worried woman on scale with wine glass and pills, low-histamine groceries visible in doorway.
Thyroid, Insulin & Metabolic Overlaps

Can Histamine Intolerance Cause Weight Gain? 5 Key Insights

You're doing everything right. Counting calories, hitting the gym, cutting sugar, drinking more water. But the scale won't budge—or worse, the number keeps...